DMi 1, Leica DMi8 inverted fluorescence tissue scanning, deconvolution microscope
DMi 2, Leica DMi8 inverted fluorescence tissue scanning microscope
Live Imaging System Zeiss Axio Observer.Z1 with Apotome 2
Light Sheet and confocal microscope
Zeiss LSM 710 Confocal. 6 laser lines, 3 detectors
Leica Stellaris 8 Confocal. White Light Laser (multiplex imaging), Lightning deconvolution, lifetime imaging, live imaging
Seahorse metabolic analysis
The Medicine Microscopy Core (MMC) provides a user-friendly, cutting-edge fluorescence microscopy imaging environment for the Columbia Medical Center in Upper Manhattan. We also provide image analysis tools, such as Leica Aivia 3D machine learning software and an Acquifer HIVE computer server and workstation. We are happy to collaborate with your imaging and image analysis projects and can provide software, custom scripting, and custom acquistion pipelines.
Click on the tabs (or icon lines) above to explore the microscopes.
Contact (replace © and •): jwm2175©cumc•columbia•edu
The Zeiss LSM 710 confocal has been repaired. I replaced both the sanning mirrors and the circiut board, and the system is working well.
2025-05-24The MMC now has SEAHORSE METABOLIC FLUX ANALYZER XFe96 and XFp instruments available for researchers at CUIMC, thanks to Dr. Hans-Willem Snoeck. Reservations can be found under "Other instruments". These are excellent systems to understand glycolytic and mitochrodrial function.
2024-12-09The LIVE IMAGING SYSTEM is now available. We have placed a Zeiss Axio Observer.Z1 live imaging microscope on the iLab calendar for reservations. Please see the specs under the "Live-imaging" link. It has temperature and CO2, 5 channel wide-field imaging as well as Apotome 2 Z-sectioning and available high speed camera for applications like characterization of ciliary beating.