DMi 1, Leica DMi8 inverted fluorescence tissue scanning, deconvolution microscope
DMi 2, Leica DMi8 inverted fluorescence tissue scanning microscope
Live Imaging System Zeiss Axio Observer.Z1 with Apotome 2
Light Sheet and confocal microscope
Zeiss LSM 710 Confocal. 6 laser lines, 3 detectors
Leica Stellaris 8 Confocal. White Light Laser (multiplex imaging), Lightning deconvolution, lifetime imaging, live imaging
Seahorse metabolic analysis
The Medicine Microscopy Core (MMC) provides a user-friendly, cutting-edge fluorescence microscopy imaging environment for the Columbia Medical Center in Upper Manhattan. We also provide image analysis tools, such as Leica Aivia 3D machine learning software and an Acquifer HIVE computer server and workstation. We are happy to collaborate with your imaging and image analysis projects and can provide software, custom scripting, and custom acquistion pipelines.
Click on the tabs (or icon lines) above to explore the microscopes.
Contact (replace © and •): jwm2175©cumc•columbia•edu
Our Leica DLS Light Sheet and confocal has been repaired, thanks to the Department of Medicine and Leica (Ghevant). I've tested the instrument, and it is working great for both confocal and light sheet work. I recomend using low gains for the best images, provided photobleaching is low.
2025-06-06The Zeiss LSM 710 confocal has been repaired. I replaced both the sanning mirrors and the circiut board, and the system is working well.
2025-05-24The MMC now has SEAHORSE METABOLIC FLUX ANALYZER XFe96 and XFp instruments available for researchers at CUIMC, thanks to Dr. Hans-Willem Snoeck. Reservations can be found under "Other instruments". These are excellent systems to understand glycolytic and mitochrodrial function.